Monday 9 November 2020

Using Accelerators

Organoids are conglomerations of cells, but the unique thing is that they are exact 3D replicas of the cancerous tumors in real human patients. In the past, we have been able to work with laboratory-generated cell lines and animals, but, for ethical reasons, it is extremely complicated to do research on human subjects. Now we can take an exact replica of human tumors outside the patient's body, look directly into them, and discover precisely what will work to kill them. Remember, Dr Goel said that each patient's cancer is individual and requires unique ways of treating it? These stand-in clones of the actual tumor give us a perfect way to discover the treatments that work as opposed to lab-grown cell cultures or animal experimentation, which may or may not reflect how a given substance might act in humans. The immensely exciting discovery from our research team is this: French grape seed extract is enormously effective in killing cancer stem cells. Let us repeat that: The OPCs in French grape seed extract killed cancer stem cells. Other than curcumin (stay with me for more on that), French grape seed extract is the only substance, natural or pharmaceutical in our experience that stops cancer stem cells from reproducing. If your balance is stable and you want to continue developing the pose, begin to slide the right foot up the leg, keeping the right knee bent and the right femur rotating outward. Draw the foot up as high as you like; You can use your hands to reach down and bring the right foot all the way up into the groin, and if you're quite flexible, feel free to bring the foot into half lotus, as long as you can keep the foot there without holding it with your hand. FIGURE 39 Ileocecal and Houston valves Draw the energy of the pose into the centerline of the body. Press the right foot into the left leg as much as you press the left leg into the right foot. Apply mula bandha to help increase the balance. Now lift your hands up into triple warmer/heart mudra, with your thumbs in the heart center and the tips of your index fingers in the throat hollow. Allow your shoulder blades to deepen into the spine as well as sink down the spine. Also allow a slight opening in the front of the chest by pressing the chest up into your hands, as if you were opening up into the space between your hands. I just don't feel like as much of a freak show, he said. I feel understood--and a lot less lonely.

Sam had a long way to go in terms of working with his trauma, but connecting with the Cheetah House community was a significant step along his journey. Having described some of the ways relationship can help survivors find safety and stability--and the way mindfulness meditation can sometimes hinder this process--I want to turn to seven modifications to basic mindfulness practice. These modifications are less focused on therapeutic skills you can employ when you're working with people such as Sam, but are structural practices you can put in place to leverage interpersonal relationships. PRACTICE IN RELATIONSHIP: TRAUMA-SENSITIVE MODIFICATIONS A screening is a preliminary assessment of a person to identify potential needs and to support their overall experience. Many mindfulness centers commonly engage in screening procedures, sending out a questionnaire to help gather information about the participant. In trauma-sensitive practice, screens are an opportunity to identify survivors who may end up struggling with mindfulness practice, opening the possibility of connecting prior to a course. The following are some standard questions you can include in a screen if the practice is a possibility. Studies show this just isn't true, though - the brain does know the difference. Scientists have even coined a new word to describe the brain's awareness of the organs - interoception. The Western viewpoint of `referred pain' goes somewhat like this. Different nerves supply different parts of the body, but if those nerves plug into the same part of the spinal cord then the brain thinks they're from the same place. It is like having two electrical devices connected to the same meter - you don't know one which is running. In the case of a heart attack it is thought that pain in the heart irritates the diaphragm and the pericardium registers and transmits pain signals. These pain signals go to the level of the third to fifth cervical nerve roots in the spinal cord. The skin supplied by these roots is over the neck and upper arm, chest wall and arm, and so the brain, not knowing which the pain is from, registers it in the wrong place or both. Instead of `confused brain theory', why not a theory of fascial propagation? If the pain is travelling down the fascia then it will be doing this in the same way that electricity radiates down through copper wires or along water. All-or-nothing. So when I think about controlling my switching--or at least learning to--it's like there's this eruption on the inside of me, that by saying `shush' to them I'm silencing them, and by silencing them I'm.

I don't know what the right word is, so I look up at her for help. I nod, and study the floor again. We sit silently, with the weight and pressure of this confession between us. I feel smothered with a simultaneous sense of shame and relief. She bends in towards me, seeking me out, because I'm closing down connection with her by huddling into my body and staring at my feet. You don't collaborate with them most of the time. You `curtail' them. So they hijack you. Talk your concerns over with your therapist. Parents: If you're an adolescent, you may wish to confide in your parents about your concerns that you may have BPD. Ideally, they will respond with empathy and concern -- as well as help you seek out professional assistance. On the other hand, they may attempt to minimize your worries by telling you that you're making a mountain out of a molehill. If your parents have typically invalidated you in this manner, they will likely do the same thing here. Some parents may also become defensive, thinking that you're blaming them for your problems. Generally speaking, we think that having this discussion with your parents is worth the risks involved. Even if their reaction is defensive or dismissive at first, they may come around in time. Besides, they may surprise you. The major exception to telling your parents about your BPD is if your parents have emotionally or physically abused you. Somewhat reluctantly, I accepted the services of a speech and communication therapist who, although not medically qualified, turned out to have considerable experience with and insight into autism spectrum disorders. This therapist was enormously helpful.

As I tried to explain how I experience the world, she listened without being dismissive. This was perhaps the single biggest turning point for me. She gently prodded me in the right direction as I worked out my problems for myself. Slowly--ever so slowly--I came to feel that maybe I was a part of the world around me after all and not so removed from it as I have always supposed. This is so difficult to put into words! There are still times when interfacing with neurotypical people is problematic for me. The old discomfort returns, along with the jangling nerves, the mutual incomprehension, and the sheer mental effort of trying to reinvent oneself, second by second, as a human presence that others can be comfortable with, rather than an absence that makes others uncomfortable. But things are getting better. When listening, the lowered spire may put your fingers in the lowered spire position. When you place your hands together, you look interested and ready to respond. Women tend to use this position more regularly than the towering spire. Confident that he has the correct answer. If you want to look confident and have all the right answers, the tilted hand's position will do the job for you. The lowered spire indicates a listening attitude. Although the cusp gesture is a positive signal, it can be used in positive or negative situations and can be misunderstood. Suppose you want to propose an idea to someone. During the demonstration, they used several positive gestures, such as open palms, leaning forward, raising their heads, and nodding. Suppose another person starts to put his hands up at the end of the presentation. That I chose to be abused, that it was my fault. Because that's easier to bear than the helplessness.

Being so powerless. I would rather be wrong, and guilty, and at fault, than be so pathetic. Here it is now: the explanation for so many of my behaviours, through the years, growing up, into adulthood. Better to be bad than to be powerless. That's the truth. We sit for a while and the rain spatters some more, like tears against the window. The scalding pain of it all begins to ebb because she sits with me. There is compassion, but she doesn't despise me. In Dr Goel's lab, we exposed those cancer organoids to OPCs and found that in just five days, the presence of cancer in those organoids was dramatically decreased. These unique studies are the only ones done using human-derived organoids. It proves that botanicals like French grape seed extract can be used for precisely targeted cancer treatments. Hippo Pathway Remember those ordinary cancer cells that have somehow acquired a superpower to transform themselves into cancer stem cells? The OPCs in French grape seed extract have that problem in hand, too. All cells, including cancer cells, communicate with each other. Think of it as an electrical network. So, what happens if one part of that network is cut? The entire network fails. Activate this lift from the upper back, not from the lower rib cage. Find a point to focus on, at eye level, and breathe deeply.

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