Wednesday, 6 May 2020

Everything is OK in the end

18 Laboratory trials with emulsions of nanoparticles coated with a novel, non-water soluble antibiotic have shown potent activity against MRSA. 19 Pharmaceutical companies are exploring the use of modified versions of older antibiotics and 'cocktails' of antibiotics in the quest to stay one step ahead of the evolving superbug. Laboratory trials of some new antibiotics show promise and there are also attempts to develop immuno-therapies and vaccines specifically against MRSA. The implementation of screening tests to detect MRSA in patients prior to admission for elective surgery has led to a reduction in hospital infection rates. Not only is MRSA causing a huge problem to human health but it has also spread to animals. We can't talk about obesity for fear of being accused of fat shaming. When the American Academy of Pediatrics put out a statement on the increasing obesity rates among children, it recommended approaching the topic using neutral words like weight and body-mass index rather than obese, fat, or weight problem. This is not to say that we should use weight stigmatization or shaming to motivate people to lose weight. Rather than motivate positive change, the stigma associated with being overweight can actually contribute to damaging behaviors such as binge eating, social isolation, avoidance of medical services, decreased physical activity, and increased long-term weight gain. So, yes, stigma is something to be concerned about. However, in our desire to avoid stigma, have we traveled too far in the other direction, protecting emotions instead of determining solutions to the problem? Of course we don't want to emotionally damage anyone; we just want them to be healthier! All of these factors combined have kept us from stating the truth: we are spiraling downward because of our own actions. If we don't change our trajectory, we are going to continue suffering from our most common (and in many cases preventable) ailments: heart attacks, strokes, and cancer. Listen, there is nothing wrong with how much space you are geared to take up. There is not a superior way to be, regardless of what messages you are picking up in the atmosphere. You do not need to be more or less; what matters is decoding what container you flourish in. This is your work, your verdict, and your line to hold.

It is upon you to insist on your space, even when it is discouraged or belittled. And here you may need some courage. When the command aimed at women is be less, the tactics include insulting, condescending, bullying, and manipulating. The goal is to make you shrink, so the maneuver will attempt to make you feel small. Your competence will be challenged, your authority dismissed, your experience questioned, your voice silenced. It is rare for a disease to cross the species barrier but MRSA can be spread from humans to animals and from animals to humans, and the collective term, zoonosis, has been adopted. The first report of MRSA being isolated from animals was in 1972,21 and since then, studies suggest that humans were the source of this zoonotic disease, as the isolates are generally the healthcare-associated epidemic strains, EMRSA-15 and EMRSA-16. 22 MRSA has mostly been isolated from dogs and horses, and in some cases, the people associated with the animals. Although the significance of this zoonotic disease in relation to public health has not been fully assessed, there is concern over the increase in the PVL toxin seen in animal-derived S aureus isolates. 23 MRSA is developing at a very fast rate, with mankind desperately trying to catch up, and there is clearly a need for systematic study and vigilance in order to gain control over infection. One initiative, in place since the late 1990s, is a sophisticated surveillance system, under which specialist laboratories in the UK, the USA and Europe collect data on suspected outbreaks of MRSA. This information helps to distinguish between HA-MRSA and CA-MRSA strains, between colonising and infecting isolates, and between new episodes and relapses of infection. 24 Each country forwards its data to a central unit in order for the collective data to be accessible by government departments tracking the spread and evolution of MRSA. The human body is constantly exposed to thousands of micro- organisms. For example, we breathe in approximately 10,000 micro-organisms daily but we only succumb to infection if the micro-organism can cause disease or when our immune system fails to protect us. If we're not careful, as is happening with type 2 diabetes and certain mental-health disorders, our children will start suffering from even more adult illnesses. Then their children--our grandchildren--will suffer further. Considering where we are now, imagine how bankrupt the system will be for our grandchildren. They may not have the resources to break our bad habits. Undoubtedly, the American health care system has its issues and inefficiencies, but it is also one of the most innovative and accessible systems in the world.

We shouldn't discourage investors from taking interest in those innovations, and we can't avoid the fact that making medical advances is expensive. Free-market competition alone won't help us out of this mess, but it's going to play a critical role. A national government takeover would halt technological progress in the medical sector. Shouldn't we instead take action as individuals to decrease the costs we can control? According to the Partnership to Fight Chronic Disease (PFCD), more than 190 million Americans, or about 59 percent of the population, are affected by one or more chronic diseases. The endgame is your feeling deflated enough to bench yourself. Happens all the time. This coercion can occur inside a marriage, extended family, career, church, friendship, or any community. With women having already internalized a lifetime of messages that they are too much, it doesn't take much browbeating to reinforce the memo. You are not required to justify your space nor hustle for approval. If someone wants you to be smaller, that is their problem, not yours. You do not need to offer a lengthy defense of your credentials or opinions. An assertive woman will always face resistance, if not early on, eventually. Some potential responses that don't include your dancing like a monkey for permission: I am more than capable for this task/work/position/responsibility. There are four major groups of micro-organisms: bacteria, viruses, fungi and parasites. The different groups of micro-organism cause different types of disease. There are other groups of antimicrobial agents that have a more general use to prevent or treat infection, inhibit growth or reduce the numbers of micro-organisms. These are disinfectants, antiseptics and preservatives. Disinfectants can be toxic to human cells so are only used in the environment to reduce the numbers of micro-organisms on surfaces.

The most commonly used, cost-effective home disinfectant is chlorine bleach. Preservatives are natural or synthetic substances that are added to products such as pharmaceuticals, paints, foods, wood, etc to prevent decomposition by micro-organisms. Natural substances such as salt, sugar and vinegar are used as traditional preservatives in food products, whereas highly toxic compounds of arsenic, copper and petroleum-based chemical compounds are used in wood preservation. Antiseptics are substances that can be applied to living tissue or skin to prevent and treat less severe or non-life threatening infections. Many are used for the prevention or treatment of malodour and skin infections. In 2016 the PFCD warned that, by 2030, the overall cost of chronic diseases in America alone was projected to reach $42 trillion. 5 Rather than trusting the government to find a solution to our mess, is there an alternative way to decrease this financial, emotional, and physical burden? We as individuals and as a society have the power to decrease prices and the prevalence of illnesses--not by making a pill less expensive, or by cutting the cost of physician visits, but by changing our own behaviors to decrease the demand. If we cut overall expenses by taking steps to avoid diseases that are in fact avoidable, we will continue to be a world leader in medical innovations, and ultimately our health care system will be more accessible, more affordable, and more efficient. The only way we can change the system is if Americans change their mind-set and admit that we are all part of the problem. Most of us take our heart for granted--beating away, every minute pumping 1. 5 gallons of blood through the body. Think of the work that this powerful muscle puts in every single minute. Yet we pay no attention to it until the emergency alarms go off. Not paying attention has a high cost: cardiovascular disease is the number one killer in the United States and worldwide. I am not asking for your permission. I am not asking for your approval. I am not asking for your opinion. I appreciate your position here, but I still disagree. I will not be bullied out of this (or into this.

) I've done the work and made my decision. I will lead/execute/create in my way. You choose to wither on command or not. Regardless of how fierce the opposition, it is your decision to own your space or concede it. Antiseptics can kill all major groups of micro-organisms when used at appropriate concentrations, depending upon the properties of the micro- organism, the presence of organic matter, the temperature and the time involved. Essential oils are nature's antiseptics. Their ability to kill microorganisms has been well-documented over the centuries. Hippocrates, the founder of medicine, used aromatic plants as early as 500 bc. Essential oils are most commonly extracted from plants of a single botanical source by steam distillation and are known to be a complex mixture of organic hydrocarbons. Essential oil hydrocarbons are volatile organic constituents of the plant matter and have related chemical structures consisting of carbon, hydrogen and oxygen. Chemical analysis of essential oils allows them to be classified depending upon the nature and ratio of components in the oil and this significant difference in chemical composition is what gives each of them their unique properties. Hydrocarbons consist of isoprene units that make up the terpenes that give the essential oils some of their antiseptic properties. Terpenes are classified as: Monoterpenes, which have 2 isoprene units (10 carbon atoms). Sesquiterpenes, which have 3 isoprene units (15 carbon atoms). Often referred to as heart disease, cardiovascular disease is an umbrella term for a group of problems that occur when the heart and/or blood vessels aren't working the way they should. It includes several conditions, with the most common in the United States being coronary artery disease, which affects the small arteries that supply blood to the heart muscle. Decreased blood flow in the coronary arteries can ultimately lead to a heart attack. Heart disease also puts you at risk of stroke, caused by decreased blood flow in the vessels to the brain. Despite the known risk factors for heart disease, many Americans remain complacent.

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